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Pathways Recommended: Metabolic Enzyme/Protease
Results for "

KPC enzymes

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125604
    WCK-4234

    		Beta-lactamase Bacterial Infection
    WCK-4234 is a potent β-lactamase inhibitor. WCK-4234 inhibits class A, C, and D β-lactamases activity. WCK-4234 lacks direct antibacterial activity. WCK-4234 potentiates imipenem and meropenem against Enterobacteriaceae with OXA-48/OXA-181 or KPC enzymes, or with combinations of impermeability and AmpC or ESBL activity. WCK-4234 distinctively overcomes resistance mediated by OXA-type carbapenemases .
    WCK-4234
  • HY-16752
    Relebactam
    15+ Cited Publications

    MK-7655

    		 Beta-lactamase Bacterial Infection
    Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity .
    Relebactam
  • HY-132987
    Avibactam tomilopil
    2 Publications Verification

    ARX-1796; AV-006

    		 Beta-lactamase Bacterial Infection
    Avibactam tomilopil (ARX-1796, AV-006), an Avibactam proagent, is an orally bioavailable β-lactamase inhibitor. Avibactam has a spectrum of inhibition of class A and C β-lactamases, including ESBLs, AmpC and Klebsiella pneumoniae carbapenemase (KPC) enzymes .
    Avibactam tomilopil

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